Adam Urbach, Ph.D.
- Semmes School of Science Distinguished Professor of Chemistry , Chemistry
I'm a native Texan, and as a college student at UT Austin I found my passions for organic chemistry, teaching, and service, and I met my future wife. I trained in the research areas of supramolecular chemistry, bioorganic chemistry, physical-organic chemistry, medicinal chemistry, structural biology, biophysics, and nanotechnology before starting at Trinity in 2004. My research group focuses primarily on biomolecular recognition – how to interact predictively with biological molecules. We have developed methods for interacting with peptides and proteins on the basis of the amino acid sequence, and we are interested in applications involving drug formulation, diagnostics, biosensors, and biomaterials. The science is interesting and fun, but my real passion is teaching organic chemistry and mentoring research students. I am also heavily invested in service to the institution and to the science community, and I am devoted to my family.
*indicates Trinity student or alumni co-author
Lilyanna Armstrong,* Sarah L. Chang,* Nia Clements,* Zoheb Hirani,* Lauren B. Kimberly,* Keturah Odoi-Adams, Paolo Suating, Hailey F. Taylor,* Sara A. Trauth, and Adam R. Urbach, “Molecular Recognition of Peptides and Proteins by Cucurbit[n]urils: Systems and Applications,” (review) Chemical Society Reviews, 2024, 53, 11519-11556, DOI: 10.1039/d4cs00569d.
Paolo Suating, Marc B. Ewe,* Lauren B. Kimberly,* Hadi D. Arman, Daniel J. Wherritt, and Adam R. Urbach, “Peptide Recognition by a Synthetic Receptor at Subnanomolar Concentrations” (article) Chemical Science, 2024, 15, 5133-5142. DOI: 10.1039/D4SC01122H. Featured as the outer back cover.
Paolo Suating, Lauren B. Kimberly,* Marc B. Ewe,* Sarah L. Chang,* John M. Fontenot,* Prakash R. Sultane, Christopher W. Bielawski, Daniel Decato, Orion Berryman, Alexander B. Taylor, and Adam R. Urbach, “Cucurbit[8]uril Binds Non-Terminal Dipeptide Sites with High Affinity and Induces a Type II beta-Turn” (article) Journal of the American Chemical Society, 2024, 146, 7649-7657. DOI: 10.1021/jacs.3c14045. Featured as a supplementary cover.
We gratefully acknowledge grants from the Welch Foundation, the National Science Foundation (CAREER, RUI, and MRI programs), the National Institutes of Health (R15 program), Research Corporation for Science Advancement (Cottrell Scholar, SEED, LEAD, and Cottrell Scholar Collaborative programs), the Camille and Henry Dreyfus Foundation, and the American Chemical Society Petroleum Research Fund.